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Given the high number of patients at risk of VTE, and the relatively simple measures which can be employed to improve patient safety, a number of National and International Best Practice Guidelines have been developed through systematic literature reviews and expert consensus panels:
| Consensus statement / guideline |
Methodology |
Recommendations relating to IPC & AES |
| NICE (UK) clinical guidelines (2010) 5 |
Evidence based guideline for England and Wales based upon a systematic literature review. |
Effective
No risk of bleeding
Can be used in combination with pharmacological methods for many groups of patients.
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| Clinical practice guideline for the prevention of VTE in patients admitted to Australian hospitals (2009) |
Developed using internationally agreed methods for the development of evidence-based clinical practice guidelines. |
AES and IPC are recommended forms of prophylaxis used alone or in combination with pharmacological methods depending upon surgical procedure, medical condition and individual patient assessment. |
| 8th ACCP conference on anti-thrombotic therapy (2008) |
North American consensus statement featuring risk stratification, recommendations and expert consensus where insufficient evidence exists. |
Mechanical methods of prophylaxis (AES & IPC) are recommended for patients at high risk of bleeding.
Recommended as an adjunct to anticoagulant-based thromboprophylaxis in higher risk patients.
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| Australia and New Zealand Working Party on the Management and Prevention of Venous Thromboembolism. Best Practice Guidelines 4th Edition (2007) |
National guidelines developed by a working party to assist in the identification and treatment of patients at risk of developing DVT. |
IPC is more effective than AES in high-risk patients when combined with anticoagulants are contrainndicated. |
| International Consensus Statement (2006) |
An international group recommending prophylactic measures in surgical, medical and obstetric patients. |
Both IPC and AES reduce the risk of asymptomatic DVT.
Combinations of prophylactic methods are more effective than when used alone.
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